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Go cellular
Studying particles in cell cultures, not in lungs: PDF
Cells cultures to replace rats in osteoporosis studies:
Mouse Embryonic stem Cell test (EST) to detect embryotoxic potential
Zooplate enabling molecular studies
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Studying particles in cell cultures, not in lungs: PDF
Cells cultures to replace rats in osteoporosis studies: 
Mouse Embryonic stem Cell test (EST) to detect embryotoxic potential 
Zooplate enabling molecular studies 